The Tumor Microenvironment and Strategies to Improve Drug Distribution
نویسندگان
چکیده
منابع مشابه
The Tumor Microenvironment and Strategies to Improve Drug Distribution
The microenvironment within tumors is composed of a heterogeneous mixture of cells with varying levels of nutrients and oxygen. Differences in oxygen content result in survival or compensatory mechanisms within tumors that may favor a more malignant or lethal phenotype. Cells that are rapidly proliferating are richly nourished and preferentially located close to blood vessels. Chemotherapy can ...
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ژورنال
عنوان ژورنال: Frontiers in Oncology
سال: 2013
ISSN: 2234-943X
DOI: 10.3389/fonc.2013.00154